This serves for a germinal centre survival signal for autoreactive B-cells. Immediately after migration to the mantle zone, autoreactive B cells need even more survival alerts from autoreactive helper T cells, which advertise the maturation of autoantibody-manufacturing plasma cells and B memory cells. Mikdashi J, Nived O. Measuring disease https://kyleraixmy.tblogz.com/5-easy-facts-about-lupus-test-described-51767620